Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This can be especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query cell identity markers sourced from PanglaoDB, CellMarker, SaVanT, MSigDB, xCell, ARCHS4, and TISSUES.
To learn more about clustermole, check an overview of the features and an example workflow starting with a Seurat object.
Image credit: “A Child’s Primer Of Natural History” by Oliver Herford