clustermole-book

Overview

Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This can be especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query thousands of human and mouse cell identity markers sourced from a variety of databases.

The clustermole package provides three primary features:

  • a database of markers for thousands of cell types
  • cell type prediction based on marker genes
  • cell type prediction based on the full expression matrix

Check the documentation website for more information.


Image credit: “A Child’s Primer Of Natural History” by Oliver Herford