Genomic analysis of model organisms often requires the use of databases based on human data or making comparisons to patient-derived resources. This requires converting genes between human and non-human equivalents. The babelgene R package helps to simplify the process. It provides provides gene orthologs/homologs:

  • in an R-friendly tidy/long format with one gene pair per row
  • for multiple frequently studied model organisms, such as mouse, rat, fly, and zebrafish
  • sourced from multiple databases
  • as gene symbols, NCBI Entrez, and Ensembl IDs
  • without a need for an active internet connection

Check the documentation website for more information.